This imposing building rises in the first stretch of Via Emilia ovest (towards Bologna) just behind the Cathedral of St. Cassiano. It belonged to the Guelph leading family of Sassatelli, and was erected around 1522 on a pre-existing building. It has a severe brick façade and a large portico-rimmed courtyard with a loggia supported by sandstone columns and embellished by terracotta decorations. Despite extensive restoration works, the paintings by Girolamo Succi, Angelo Gottarelli and Antonio Villa which decorate the vast rooms are still visible. 
In 1501 Guidarello Guidarelli was killed during a ball held in this building.